Filtered by Category: AxD Research
LATEST NEWS
AxD RESEARCHPranam Chatterjee, recipient of EndAxD funds to study AxD, receives NIH grant to expand AI platform to target diseases
September 17, 2024
"The EndAxD award was instrumental in getting the NIH grant and the projects are very complementary. The results of the R35 will help us be more specific in targeting GFAP and I look forward to continuing to work on Alexander Disease with our research." - Pranam Chatterjee | Read Full Article Here |
Astellas Announces Sponsored Research Agreement with UMass Chan Medical School
June 27, 2024
Astellas Pharma US, Inc. has teamed up with UMass Chan Medical School to advance research on a groundbreaking gene therapy for Alexander disease, an ultra-rare and fatal condition. This innovative collaboration aims to bring new hope to patients through adeno-associated virus (AAV) vector-mediated therapy. The research, led by Dr. Jun Xie and Dr. Guangping Gao at ...
Empowering Families Affected by Alexander Disease Through Groundbreaking Research
March 15, 2024
We are excited to share that End AxD has funded the innovative research conducted by the Chatterjee Lab at Duke University. As part of our ongoing commitment to supporting families affected by Alexander Disease, we are proud to contribute to the groundbreaking work of this esteemed research team. ...
United Leukodystrophy Foundation Conference '23 - AxD Session Links
September 8, 2023
Hey Alexander Disease Community! We're excited to share some highlights from the recent United Leukodystrophy Foundation conference, where the latest advancements in Alexander disease research and treatments were shared. Here's a recap of the sessions you won't want to miss:1️⃣ Alexander Disease Insights 🧬Learn about the most recent research breakthroughs and ...
Webinar Recording Available Now: AAV-medicated Gene Silencing (August 2023)
September 7, 2023
If you weren't able to join us on Sunday, August 6, 2023 for Dr. Gao’s update regarding “AAV-mediated Gene Silencing for the Treatment of Alexander Disease” the recorded version of the webinar is now available! Watch Recording Here
End AxD funds gene therapy research for Alexander disease
April 2, 2023
The foundation End AxD, a nonprofit dedicated to research, treatment and a cure for Alexander disease, has donated $74,000 to UMass Chan Medical School to explore a gene therapy treatment for the fatal neurological disease.
Waisman Center: Alexander Disease
August 19, 2020
Alexander disease, a leukodystrophy, is a progressive and usually fatal neurological disorder in which the destruction of white matter in the brain is accompanied by the formation of abnormal deposits known as Rosenthal fibers. Rosenthal fibers are aggregations of protein that occur in astrocytes, which are cells that support the brain. These protein collections are ...
Rare Disease Database
August 19, 2020
SummaryAlexander disease is an extremely rare, usually progressive and fatal, neurological disorder. Initially it was detected most often during infancy or early childhood, but as better diagnostic tools have become available has been found to occur with similar frequency at all stages of life. Alexander disease has historically been included among the ...
Genetics Home Reference: Alexander Disease
August 17, 2020
Alexander disease is a rare disorder of the nervous system. It is one of a group of disorders, called leukodystrophies, that involve the destruction of myelin. Myelin is the fatty covering that insulates nerve fibers and promotes the rapid transmission of nerve impulses. If myelin is not properly maintained, the transmission of nerve impulses could be disrupted. ...